mTOR inhibitors like RTB 101 may reduce the risk of upper respiratory tract infections in older adults.

“so in our face tube we said let's not only look at vaccine response but let's actually look at infections that occur to see are we decreasing infection rates and in that phase tube we also said if mtor inhibitors really do enhance immune function this shouldn't be specific to a wrapalog which is a drug that changes the confirmation of mtor and that's how it inhibits it and we said other kinds of mtor inhibitors which block the catalytic site and towards an enzyme in it they block the catalytic site they should also have benefits if this is really an mtor mediated effect”

“so in our phase 2a we saw that the benefit for rtb was better than for a vera leibniz”

“the quote is something to the effect of rapamycin could reduce the morbidity of covid19 by 50 percent maybe it's out of context i'm referring to jones a phase 2b study where severe disease was decreased by 52 am i right”

“what was really striking was a lower risk of upper respiratory tract infection in the people who'd gotten the mtor inhibitor over the next season”

“one of the effects of everolimus and another drug called rtb 101 which is also an mtor inhibitor is to boost antiviral gene expression”