Ketamine treatment in individuals with alcohol problems showed reductions in rumination and anhedonia at three months, with anhedonia returning to baseline by six months, while drinking reductions persisted.

“what we found that i think is interesting is we were still seeing impacts on like reductions in rumination which i meant that repetitive negative thinking and reductions in anhedonia which is a hallmark of depression but also across multiple disorders and that's an inability to experience pleasure in the world and um so we saw reductions in that at three months but they were back to baseline at six months whereas they were still showing reductions in drinking which is i thought was really interesting”