The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
and the guide r separate these are okay separate and it's amazing that once those cells acquire both the MRNA for cast 9 and the MRNA that is corresponding to the guide it will it will translate into a cast n protein it doesn't translate guide RNA into a protein it just stays there and they find each other
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
and these cells are going to be U sort of modified in the laboratory uh where researchers will take the the RNA the the messenger RNA for cast n so this will allow the cell to produce the cine protein and they will also take the guide RNA
and this is actually how people uh treat CLE cell disease except they're not putting DNA into the cell they're putting mRNA so they incubate um these boneo stem cells that have the CLE cell mutation in a bath of mRNA for cast n and the guide RNA