Phase two clinical trials determine the right dose and schedule, correct patient population, and appropriate outcome measures for phase three trials.

“phase two I think is um that's where people can use their intellect I think in many ways phase two you start to look at what's the right dose and schedule um very very important to get the right dose and schedule and what what's the right outcome what's the right patient who do you want to treat and and really what phase two is supposed to do is with one exception phase two is supposed to get you ready for phase three you've got a dose you've got a schedule you've got a patient selection criteria and you've got a hypothesis of where this is going to be a drug”