The Vioxx trial in 2011 included 55% of patients taking corticosteroids, a group not representative of the general population prescribed the drug.

“and um in that study that I was talking about before the bigger study that was designed to show that Vox caused fewer GI complications they rigged the patient population so that 55 percent of the people who were in that study were taking corticosteroids like Prednisone for arthritis now that's in a normal population less than three percent of the people are taking corticosteroids uh in conjunction with anti-inflammatory medicines but in this study 55 more than half were taking corticosteroids plus an anti-inflammatory drug”