Peter Attia· MD
that's what everybody always focus on everybody since low HDL cholesterol is a risk factor who we now know april-b related but whatever therefore if low HDL cholesterol is bad raising HL cholesterol has to be good
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
that's what everybody always focus on everybody since low HDL cholesterol is a risk factor who we now know april-b related but whatever therefore if low HDL cholesterol is bad raising HL cholesterol has to be good
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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if we look at the effect of niacin on raising hdl which it does right hdl cholesterol goes up with niacin administration at a high enough dose but the outcome trials are very clear that that does not translate into benefit it makes you think a little bit of the c-tep trials where you give a c-type inhibitor hdl cholesterol goes up in some cases you actually saw more events but usually at best you see no effect there