Peter Attia· MD
Now ibuprofen uh Advil alie for example are considered category B in the first two trimesters but bump to category D in the third trimester for reasons I don't necessarily need to get into but for those who are interested it has to do with the premature closing closure of a very small blood vessel that connects the aorta and the uh pulmonary artery and if that closes prematurely it leads to premature delivery and all sorts of things like that.