Peter Attia· MD
um we also use Topiramate which is a seizure medication which was first first discovered off label to be helpful for binging disorder and um later was shown to be helpful for alcohol use disorder but the bottom line is when we have a case of a patient who has tried these various medications who's been involved in Alcoholics Anonymous who's tried Psychotherapy who's gone to rehab who's done it all um in that rare instance because it is off label and because it's so new and so we we are conservative with medications we will occasionally we have occasionally recommended suag glutide or the glp1 um drugs and um in one case in particular it was very striking the extent to which this individual with treatment refractory alcohol use disorder indorsed the complete cessation of alcohol craving um with uh semaglutide and you know it's it's very moving to see that in an individual who has struggled so long long and so hard uh to battle their addiction and then there's this drug that seems to um just suddenly turn off all the noise for them