Cyclosporine prevents organ transplant rejection by inhibiting IL-2 secretion after T-cell receptor binding.

“what eventually was discovered is that it was interfering with the cascade that occurred when that foreign antigen was presented to the recipient t cell and [Music] in other words it was a more selective immunosuppressant so directly interfering with the cascade of events that happens downstream of the t cell receptors and it specifically inhibited il2 secretion it it affects il2 secretion”