Probiotics may be beneficial in depression, likely by influencing the gut microbiome's effect on the brain, but dietary changes are a stronger modulator.

“there are some studies that suggest that probiotics can be beneficial in depression and I think that in those studies were hitting on something here and the idea that we're hitting on there is that the gut microbiome does affect the grade okay that is all I think that those studies suggest I don't think those studies suggest that we need probiotics and I don't think those studies suggest that those probiotics are doing anything unique because I would argue that dietary changes are the strongest way to alter”