After exercise, muscles prioritize sufficient building blocks over signaling for protein synthesis because the signaling pathways are already fully activated.

“it's those amino acids are more than building blocks they're also signaling molecules that directly stimulate muscle protein synthesis so they directly activate um the empor pathway driving muscle protein synthesis”

“and of course how I translate it is when you perform physical activity the muscle is more interested in having enough building blocks than the signaling process because the signaling process has already been fully activated by the exercise”