The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
the branched chain amino acid and methionine restriction studies are are pretty clear that those animals are consuming more calories more calories than certainly if you matched a weight then they add little mice and they're living longer
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
or you can restrict specific amino acids particularly branched chains tryptophan methionine or branched chain amino acids are the ones that have been studied
The common mechanis is M that that does seem to uh potentially underly all of these forms of protein restriction is inhibition of mtor
I think there it's pretty clear that you can extend lifespan through protein restriction and there are actually again a couple of flavors of protein restriction you can restrict all protein down to you know some some percentage some low percentage um or you can restrict specific amino acids particularly Branch chains Tri tryptophan methionine or Branch chain amino acids are the ones that have been studied
This idea stems largely from laboratory studies showing that restricting protein intake extends lifespan in animals and observational data linking High animal protein diets to a higher mortality rate