The relationship between protein intake and health during aging in humans may differ from that in mice.

“on the one hand there's this body of mostly kind of animal literature that suggests lower protein intake is associated with a longer life but on the other hand there's this literature that says lower protein intake is associated with more Frailty in humans and that's associated with a shorter life”

“I think that my view is there are probably multiple paths to longevity and we really don't understand the the inner relationships of these macronutrients in in the diet with enough sophistication to to get Beyond sort of broad General predictions and again you know I sort of this is an area where I I really I believe like I can't prove it but I my intuition from uh from the data that I've seen and just my observations of people is that in humans it's probably very this relationship between protein and health during aging is probably very different than it isn't in mice I think mice are able to tolerate a very low protein diet without you know some of the consequences that we see in people that's my intuition I don't you know I I don't know that that's true”