Laboratory mice do not experience the same catabolic crisis events as humans, making direct comparisons of protein restriction benefits between mice and humans unreliable.

“People are not mice, right? We, like we talked about earlier, um, as we get older, we're being exposed to infectious diseases. things are going to make us immobile for a period of weeks and that is devastating to us especially when you add them up and they happen this year and then the next year it happens again and then you're just losing that muscle mass right and then you reach that disability threshold you talked about Luke Vanlon um talking about those curves it's very clear I mean you can see the data where there's a disability threshold you get enough of these like catabolic crisis events right where you're just immobile for a certain period of time because you've had a surgery or you've had the flu or whatever kept you inactive. Um, that doesn't happen to these mice, right?”