The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
the other player that seems to be important particularly in um total protein restriction is a protein called fgf21 fiber fibroblast growth factor 21 that is uh secreted in response to a low protein diet and then has effects on liver metabolism and and also inhibition of mtor reduction of igf-1 so that seems to be required for the lifespan extension that is seen from protein restriction in mice
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
the interesting thing there is fgf21 overexpression by itself has also been reported to be sufficient to extend lifespan in mice