Peter Attia· MD
where they work on the 5ht to a receptor and ketamine as we were talking about works on these kind of glutamatergic receptors
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
where they work on the 5ht to a receptor and ketamine as we were talking about works on these kind of glutamatergic receptors
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
but there may be a glutamate modulation of this system and ketamine, as I'm sure you know, has been shown to actually have very significant antidepressant effects and treatment-resistant depressed patients, at least a subtype of them.
And it could be that we're going to have a convergence of some kind of mechanistic thing in common with the classic hallucinogens.