Psilocybin administration to vulnerable cancer patients with significant anxiety or depression resulted in large and sustained decreases in these conditions.

“And the results really were quite striking. They confirmed everything we had seen in the healthy volunteers that is these very vulnerable cancer patients who had very significant anxiety or depression experience the same types of...experience is very often classified as this mystical-type experiences, but they were deeply moved by these experiences.”

“interestingly uh these people experienced very large and sustained decreases in anxiety and depression and and those effects occurred really quite promptly after the administration of the drug and although the design of the study was such it was a crossover design so people were crossed over between essentially an inactive dose of psilocybin to an active dose or vice versa so so the strongest conclusion we can make comparing our our placebo condition and our active condition is this effect lasted out to five weeks but uh in fact we followed people out to six months and there was no evidence that there was any um significant uh rate of relapse over that period of time so in other words most people who demonstrated a large therapeutic effect remained having low levels of anxiety or depression out to six months”