The majority of off-label rapamycin users surveyed take it once a week, with 6mg being the most common dose.

“but um by far the majority were once a week and among those the vast majority were 6 milligrams once a week and I think there's some historical reasons for that that sort of you know has what become become popular in the the online sort of community where people talk to each other but where do you think that number comes from so I think it's partly from Janes study so it's close to Joon study which was 5 milligrams once a week of ever alus I think it's also because many of the people the first people to start taking uh rapy off label were patients of Alan Green out of New York and I think that was sort of his standard dose that he put most people on so I could be wrong about that but that's my impression is that's kind of how that became popularized for lack of a better word within the within the community but having said that there are there's a lot of variation around that both in terms of doses that people are taking once a week and then there's a you know fraction of people who are taking rap ayon daily um uh usually one milligram 2 milligrams um sometimes for you know purposes other than purely for aging so people who have uh existing autoimmune disorders sometimes people are taking rapamycin for that but um but in general I would say among the off Lael rapy users the majority are once a week and of those the majority are 6 milligrams um kind of it's kind of a bodal distribution there's a group of people around 3 milligrams as well but lots of variation around that”

“most people using ramyon off label for potential Health span effects most doctors prescribing it are recommending once weekly dosing you know in the 3 to six sometimes 8 10 milligram range”