Rhonda Patrick· PhD
And one example that is well known is resveratrol contained in red wine that induces autophagy through this pathway.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
And one example that is well known is resveratrol contained in red wine that induces autophagy through this pathway.
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And then the other thing that was interesting, as you know, was the autophagy because resveratrol seems to be activating autophagy and I also interviewed Guido Kroemer on the podcast. And he talks about these three signals that are important for autophagy, and one of them is the increase in protein... Oh, wait, decrease in protein acetylation? Yeah. Because sirtuins are histone deacetylases. So that would lead to, right? A decrease in protein acetylation.
And one of the enzymes that they work on is an autophagy protein that goes and destroys bad protein. So it's perfectly reasonable to think that if you take resveratrol, it might be clearing the body of those proteins.