Resveratrol was heavily hyped as a longevity agent but evidence suggests it does not extend lifespan in mice and its proposed mechanisms of action are questionable.

“Resveratrol was was hyped um for uh many years people often with commercial interests or who had a grant or who wanted to get a lot of money for clinical trial with start their talk with a beautiful bottle of red wine and then say Resveratrol is in red wine and cerin are uh important and Resveratrol influences cerin and just take some of my Resveratrol or cerin activating agent and you'll live forever none of that was right I mean it's been shown very clearly now that the amount of Resveratrol and red wine uh is to get enough of it you need to uh drink 30 bottles a day it status as a cin activator has been questioned by very serious and skilled biochemists the original data on worms has been disconfirmed by a couple of very good Labs”

“has a good PR team I think it's really hard to prove something doesn't work right so once it gets in the Consciousness as as improving health I mean even in the longevity field Jesus Christ I was saying the Resveratrol stuff was garbage for 10 years before people believed it right now everybody believes it but takes a really long time”

“For example, um I don't remember exactly when GSK bought um Rveratrol. Yeah. But I believe it was like around 2006, 2007. Yeah. uh you know I I it was clear to me I think by about 2010 that that was not going to work and and I think it was probably clear to GSK around that time as well.”

“But unfortunately that coupled with the uh rveratrol fiasco uh and I I really unless you think otherwise Eric we don't need to talk about rveratrol but I I am I remain completely convinced that rveratrol had zero benefit whatsoever. I think it is an absolutely uh useless molecule. Um so I think that rveratrol debacle um the overhype complete debacle of that coupled with the fact that all of the participants in the NAD landscape are doing it through their own commercial enterprise with their own proprietary blend has has resulted in this inability to drive forward in this field.”