The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
what the mutation did was it made an enzyme that couldn't be moved it had a stiff elbow and without the bending of the protein at the elbow resveratrol couldn't activate it anymore and we know this very clearly it's been well published in cited
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
and we found that was true the drugs that were in development the super potent ones also blocked by this one mutation what the mutation did was it made an enzyme that couldn't be moved it had a stiff elbow and without the bending of the protein at the elbow resveratrol couldn't activate it anymore
we had a science paper published in 2013 where we went to the effort making a finding research for a mutation in a cert one gene that we had published is likely the way research all works and that mutation blocked resveratrol his ability to activate the sirtuin enzyme