David Sinclair· PhD
RSV-metformin reduced lipid accumulation and the expression of lipogenic [fat making] genes in palmitic acid (PA)-induced HepG2 cells.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
RSV-metformin reduced lipid accumulation and the expression of lipogenic [fat making] genes in palmitic acid (PA)-induced HepG2 cells.
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This combo protected HepG2 cells against PA-induced cell death by turning on autophagy.