The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
at the age of 75 there is a cliff that is so violent you can't believe what you're watching and at it's at that Cliff where physical activity level declines like this it just goes boom muscle mass goes Doom strength Doom same thing and you know of course it begs the age-old question right is the patient losing strength because they are no longer active or are they no longer active because they have lost strength my view is it's both I think these things feed off each other
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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is the patient losing strength because they are no longer active or are they no longer active because they have lost strength my view is it's both I think these things feed off each other um which one's the first insult I suspect it's probably the loss of strength that contributes to the loss of activity but then I think those feed
now of course this figure cannot give us causality I can't look at this figure and tell you that the reason physical activity level falls off a cliff at 75 is because muscle mass does the same nor can I tell you that muscle mass is declining because physical activity goes down but it's hard for me to imagine that What's Happening Here is not um bidirectional in other words I suspect that what's happening is that at 75 or thereabouts for the average person activity declines and as activity declines muscle mass declines and as muscle mass declines activity declines further and these things spiral out of control
and you know of course it begs the age-old question right is the patient losing strength because they are no longer active or are they no longer active because they have lost strength my view is it's both I think these things feed off each other um
but of course in one person it might be the cardiovascular decline that is driving the muscle loss while in the other person it's the muscle loss driving the cardiovas decline