Peter Attia· MD
what you're actually seeing is that the calorically restricted mice have maintained muscle function proportionate to their body weight
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
what you're actually seeing is that the calorically restricted mice have maintained muscle function proportionate to their body weight
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I think the important complication here is that all of the caloric restriction studies that I'm aware of when they look at muscle function normalized yeah and the calorically restricted mice weigh substantially less than the ad libidum fed mice usually I think it's on the order of 30 35 yes so yeah so it's usually grip strength normalized to weight right so what you're actually seeing is that the calorically restricted mice have maintained muscle function proportionate to their body weight
all of the caloric restriction studies that I'm aware of when they look at muscle function normalize to body weight