Human skeletal muscle fibers are multinucleated, possessing thousands of nuclei per cell.

“um in fact I whenever I talk to biology people about this that like their head is blown because I forget how lost in exercise science I get like us nerds but it's it's very uncommon in nature to see cells that have more than one nucleus and the nucleus is the is the the core or the cell if you will that's what holds your DNA that's what controls and tells you when to replicate proteins um to grow shrink D repair so the whole control center so the fact that skeletal muscle has many of them per cell in fact it's not a few it's not two or three it is Thousands per cell so skeletal muscle can be extraordinarily large um”