Peter Attia's clinical framework for assessing patients involves determining if they are overnourished or undernourished, under-muscled or adequately muscled, and metabolically healthy or unhealthy.

“if i'm looking at a patient i'm asking a question are you over nourished or undernourished are you under-muscled or adequately muscled and then on so that's a two by two right and then are you metabolically healthy or not that's sort of my first order question”