Peter Attia· MD
I think the first time that uh anabolic resistance was was published as the name was coined was by uh by the people in dunde Mike reny the late Micra so he did a study where he provided essential amino acids to people young and elderly and when they provided a greater amount of essential amino acids you saw in the young people a greater muscle protein synthetic response as we discussed before he got he got the greatest response the highest muscle protein synthesis following the provision of 10 grams of essential amino acids which is perfect because 10 grams of essential amino acid translates to about 20 grams of protein so it nicely fits with those other studies if he gave 20 grams of essential amino acids there was no significant further increase over the next few hours so that was normal response and in line with everything that we discussed before if he did the same thing with the older population he saw that that increase in muscle protein synthesis was less Steep and also leveled off more rapidly so that's how he coined anabolic resistance and that was I think 2005