Peter Attia· MD
I once had a patient coming in saying that they were taking 450 milligrams of bupropion for depression before bed no right that's going to be a pretty stimulating dose of something to take for a bed
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We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
I once had a patient coming in saying that they were taking 450 milligrams of bupropion for depression before bed no right that's going to be a pretty stimulating dose of something to take for a bed
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
For example I once had a patient coming in saying that they were taking 450 milligrams of bupropion for depression before bed No Right That's going to be a pretty stimulating dose of something to take before bed
10 minutes of bright outdoor light within the first hour of waking anchors the circadian phase and improves sleep onset that night.
Morning sunlight exposure shifts the cortisol awakening response forward, improving daytime alertness.
Long-term morning sunlight reduces age-related macular degeneration risk.
Sleep regularity predicts all-cause mortality more strongly than sleep duration.
Tracking deep sleep on a wearable accurately reflects EEG-measured slow-wave sleep.
Caffeine has a half-life long enough that consumption after 2pm measurably degrades deep sleep in slow metabolizers.