And what we notice is that when you sleep more, your cortisol levels are lower. And cortisol, of course, is cortisol and epinephrine, and all of these other beta-adrenergic systems affect the G protein. Stimulate the G protein causes increasing cyclic AMP in these immune cells. And they make those proteins like the major histocompatibility complex 1 and 11, less sticky, and so it impairs your immune system when you have higher levels of cortisol, higher levels of stress.