in fact if there's anything that we've seen that xyrem seems to be detrimental to it's actually these things called sleep spindles now sleep spindles are these short synchronous bursts of electrical activity that happen during non-rem sleep they last for about a minute or a minute and a half and we know from the work that we've done and other people have done they are critical for things like learning memory and brain plasticity and what we found is that when you take ghb or xyrem the amount of sleep spindle activity is decreased