The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
and the statin trials and we don't see that at all in fact we don't see that clinically either there's no dose response in terms of these in terms of LDL lowering when we lower LDL very low it's not weigh less atherosclerosis than if we lower LDL a little bit
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
And then we look at the statin trials, regardless of the way that LDL cholesterol gets lowered, and there's different statins that work different ways, um, it is the same dose response, which is about 22%.