Paul Saladino· MD
one particular L was associated with significant increase in risk of new diabetes since the statins inhibit HMG COA reductase as their motive action this may at least partly explain their diabetogenic effect
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
one particular L was associated with significant increase in risk of new diabetes since the statins inhibit HMG COA reductase as their motive action this may at least partly explain their diabetogenic effect
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they say here this is Statin induced diabetes incidents mechanisms and implications is the study it's from gan in 2016 they say an exciting new observation exciting gentic polymorphism leading to A reduced activity of HMG COA reductase this is the enzyme that statins block is associated with lower ldlc a significant increase in body weight and features of insulin resistance this observation was valid validated in the randomized stand Statin trials and one particular L was associated with significant increase in risk of new diabetes
they they say here this is Statin induced diabetes incidents mechanisms and implications is the study it's from gan in 2016 they say an exciting new observation exciting gentic polymorphism leading to A reduced activity of HMG COA reductase this is the enzyme that statins block is associated with lower ldlc a significant increase in body weight and features of insulin resistance