While up to 30% of patients report muscle symptoms with statins in real-world practice, randomized clinical trials show no difference in muscle symptoms between statin and placebo groups.

“we know in real world practice you know up to 30 percent of Statin treated patients will report muscle symptoms so there's this tremendous nocebo effect in Trials like the Samson trial up to 90 percent of Statin Associated symptoms was elicited by the placebo too”