The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
So we spend, as a country, you know, tens of billions of dollars every year on this drug that you mentioned, LDL-lowering drugs like statins, and this, as far as I understand, is on the premise mostly that when someone goes to get their lipid panel measured from their doctor, from their primary care physician, it's based on their total LDL cholesterol, because most physicians do not measure all the different particle sizes of LDL cholesterol.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
And so that's because there are a set of LDL particles that are lowered by statins that are bad. And so it's not as if it's all or none, it's just statins could be more effective if they were able to lower the smaller particles.