Hydrophilic statins were once thought to be safer than lipophilic statins, but this distinction may be less relevant now.

“where did all this hydrophilic lipophilic stuff come from the first two competitive statins on the market were Simba Statin which was MC's most potent Statin more potent and their Lovastatin or meore so everybody jumped on zil Cor or simvastatin but Bristol Meer squid made pravastatin hydrophilic and there was a lot of thought looking at other biomarkers that the and even catabolism that the hydrophilic statins were safer than the others”