A combination of a statin and ezetimibe can provide the same ApoB reduction as maximizing statin therapy alone, and this combination has outcome evidence.

“with and most people baby statin and as etem I will give you the exact same april-b reduction of your gorillas stat and we have outcome evidence and knee improve at trial that is that um I've been statin for the guy so I gotta see outcome data”

“rather than maximizing a statin using the gorilla dose day one i would prefer to start with a smaller dose again depending on your risk and your metrics i mean if you're coming off an acute coronary syndrome and your ldl metric is off the chart okay i'll start with a big but i'd rather take that baby statin meaning a lower dose of a statin and perhaps optimizing it with a second apob lowering drug”

“so we're very quick to Pivot patients off statins if we can't get great efficacy with no side effects at low dose”

“you take a baby Statin my sort of acronym for a lowd do Statin and you combine it with a zmi bidic acid or P ps9 inhibitor you've got a uh a military machine that can destroy AO B”

“we can get most of the apob B lowering with a Statin with the baby dose this has been proven in trial after trial most of the LDL receptor upregulation occurs with the lowest dose that inhibits cholesterol synthesis you start doubling tripling quadruple you might get another 6 7% not the original 30% lowering or so”

“you take a baby Statin my sort of acronym for a lowd do Statin and you combine it with a zmi bidic acid or p p sk9 inhibitor you've got a uh a military machine that can destroy APO B”