Paul Saladino· MD
if you look at the 4s trial one of the original big statin trials those who had a low triglycerides or HDL ratio did not get a benefit from taking a statin
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
if you look at the 4s trial one of the original big statin trials those who had a low triglycerides or HDL ratio did not get a benefit from taking a statin
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
if you have a coronary artery calcium score of zero or less than 100 then you don't get don't get an overall statistical benefit from a statin