A small increase in Lp(a) levels due to statin therapy should not deter prescribing statins, as they are effective and beneficial, especially in patients with high Lp(a).

“Statins do not affect the synthesis of the larger apoa moiety so in some people peter says statins do not much to lp little a concentrations but there is a small component where statins will actually raise it a little bit and people get scared they go well i'm lowering ldl cholesterol ldl particle are tab but i'm raising lp little a even samsumikas will tell you don't worry about it lp little a if you learn nothing else about our lp little a discussion is a minority ldl particle so even though if you have the small isoform of statin maybe raising lp little a a tad it's so blowing away the ldls that don't have apoa attached to it that at the end of the day you have less cardiovascular risk and that little excursion in lp little a concentration is probably meaningless”