Peter Attia· MD
Retrospective study showing that those with CAC = 0 derived no benefit from statin treatment in a follow-up of nearly 10 years.
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Retrospective study showing that those with CAC = 0 derived no benefit from statin treatment in a follow-up of nearly 10 years.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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and for people who have a zero calcium score who are at relatively low risk we do the mesa risk calculator or the asc 10-year risk and they're under seven lots of times they're one or two or three like it's hard to improve somebody who's got such a low risk and in them i say you know let's not get overly shook up about your ldl and let's just you don't need to stab and we can stop your sound we don't need to start it whatever and we'll focus on diet and extra lifestyle
there's a lot of people who have high cholesterol and high blood pressure bad family history just a frightening array of risk factors you do a calcium score on them and it's zero and you say well we've gotten through 53 years of life without making any hard plaque so we're not gonna like we maybe don't need to use a statin on you maybe we don't maybe we can tolerate it seems like you're doing fine
that's sort of the subtle but important difference between the Staten star because the people on Staten star already by definition on the the on the risk reducing therapy that's been shown to save lives so like it's uh it's not like what are you going to do to that person because their calcium score is higher you know would you be more aggressive