Statins, first approved in 1988, became an important mainstay in treating stable coronary disease, coinciding with the advent of the stent era.

“The first statin, lowest statin was approved in 1988, I believe. So- Remember I had said that we were treating people with angina with basically beta blockers and nitrates. And so then statins got added to the mix. They weren't initially added for treatment of stable disease. They were there for, they were initially tested in people who were having unstable disease, but it quickly became obvious that they were going to become an important mainstay of treatment of people with stable coronary disease as well.”