Paul Saladino· MD
the 4S trial the subgroup of which I showed you earlier had an LDL reduction of 25% and a mortality benefit of 3.3% that was an absolute risk reduction in all CA mortality from fors trials
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
the 4S trial the subgroup of which I showed you earlier had an LDL reduction of 25% and a mortality benefit of 3.3% that was an absolute risk reduction in all CA mortality from fors trials
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.