Desmosterol, a marker of cholesterol synthesis, should ideally be above 0.5% when other factors are equal.

“using desmos trawl as a continuous variable and using a statistical technique called receiver operating characteristic curve production they showed that once desmos trawl fell below 0.5 the AUC the area under the curve of the receiver operating characteristic was somewhere between 0.8 and 0.87 depending on the study and depending on gender”