It is uncertain whether rapamycin, at doses that extend lifespan, would impair the ability of animals to build muscle mass if subjected to a resistance training regimen.

“I don't think we have any data in humans on people who are just doing resistance training in the context of just wanting to maintain muscle mass or build a little bit of muscle mass as they're getting older I just don't think don't think we have that data and I don't think we have the data in rodents to really answer that question either in the context of the doses that extend lifespan would that impair the ability of those animals to build muscle mass if they were put on some sort of a resistance training regimen”