The increase in protein degradation during resistance training significantly decreases after approximately six weeks, coinciding with the onset of noticeable hypertrophy.

“in the initial kind of phases of training you have an increase a robust increase in muscle protein synthesis but you also have a very robust increase in protein degradation and so the thought process is because this is such a big stressor a massive stressor if you've never resisted trained before i mean everybody knows like the first time they went did a leg workout you couldn't walk for like a you know a few days after that you have to completely it's almost like your muscles doing a complete overhaul of those of those proteins and so you have such a robust degratory response because there are so many damaged proteins or or proteins that need to be i guess improved then it's almost like you're you're doing this protein turnover feudal cycle um kind of remodeling”

“what we see is after 6 weeks that at the end of 6 weeks that increase in degradation goes way down and that's actually I mean again I can't say for certain but it coincides with when we start seeing the big improvements in hypertrophy”

“during the first approximately six weeks of resistance training You Don't See Much hypertrophy in people who are training you see strength improvements but you don't really see hypertrophy”

“in the initial kind of phases of training you have an increase a robust increase in muscle protein synthesis but you also have a very robust increase in protein degradation”