Peter Attia· MD
if we look at myofibrillar protein synthesis in response to resistance exercise we see what tends to happen is the amplitude of muscle protein synthesis in trained people is a little bit lower than untrained um the it depends on when you measure if you measure at 16 hours post you're they're about the same they're about a 40% increase if you measure at four hours post there's about a trained is still about 40% untrained is about 70% so you've got a little bit of difference in amplitude but what really is the difference is the duration so in trained people it's back down to Baseline about 10 to 20 hours after the initial resistance training bout whereas the untrained people still have elevated rates of protein synthesis even like 3 days or even like two three days later