Sulforaphane extended lifespan in red flour beetles, particularly under oxidative stress.

“So there's a red flower beetle. Yes, it's a bug, but they have an Nrf2 gene that's homologous to humans, also the FOXO gene, as well. So the scientists fed these red flower beetles different doses of broccoli sprout extract and the doses ranged from, it was low to high, I can't recall, but it was a dose response. And what they found is that at, I think it was at the highest dose, it extended the lifespan of these beetles by 15% and when they exposed these beetles to a high oxidative stress all the time by keeping them in a warmer environment constantly, it extended their lifespan by 30%. And it was totally dependent on Nrf2. So if they knocked down Nrf2, the lifespan extension went away.”