Rhonda Patrick· PhD
It up-regulates its production. So if you look at RNA levels for Nrf2 or for Keap1, it's tether protein that's present in the cytoplasm. After treatment with sulforaphane, you see those levels going up.
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
It up-regulates its production. So if you look at RNA levels for Nrf2 or for Keap1, it's tether protein that's present in the cytoplasm. After treatment with sulforaphane, you see those levels going up.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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Under normal conditions NRF2 is briefly activated every 129 minutes. However, when stimulated by sulfurophane its activity pattern changes. It becomes activated every 80 minutes which is about a 61% increase.
i know that the animal studies have shown that the nrf2 protective pathways activated for at least two days