Consuming excessive amounts of 1,3-butanediol can overwhelm enzymatic degradation pathways and lead to the generation of harmful aldehyde intermediates. — Whalespan
Consuming excessive amounts of 1,3-butanediol can overwhelm enzymatic degradation pathways and lead to the generation of harmful aldehyde intermediates.
⚠ High risk
We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
✕NOTSUPPORTED
⚠
High-risk intervention — consult a physician before acting.Drug-drug interactions, dose-dependence, and screening contraindications apply.
“But you know in getting back to 13 butane dial if you consume it and you consume large amounts of it uh like some of the early work that was done by you can overwhelm that enzyatic cascade and you can start generating you know a lot of these aldahhide intermediates and that's maybe not a good thing.”
“Uh you are generating a beta hydroxybutyrate aldahhide that is relatively short-lived, but you can overwhelm the ADH enzyme. So by if you drink too much of it you can cause uh you can overwhelm the enzyatic degradation and Henry Bruningraber did some seminal studies on this that he shared with me some of it's published they had a they had a ketogenic dog model that they gave 13b butane dial is a hypoglycemic agent.”