Exogenous ketones lower blood glucose, and high doses of ketone esters in rats can significantly lower glucose levels.

“in his study where rats were fed standard rodent chow but 30 to 20 percent ketone Esther I think within that Chow their baseline insulin levels went down like 50 percent so that's just simply by you know just the addition of via tome just the addition of the ketone over time over I think it was like it may be a three week I got to look to see the study but it was it was consuming ketone Esther that was integrated into the rat chow over a number of weeks decreased baseline levels of insulin significantly I mean it was like a huge effect”