Peter Attia· MD
dht is something that is converted from testosterone using an enzyme called 5-alpha reductase
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dht is something that is converted from testosterone using an enzyme called 5-alpha reductase
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These hormones will go up now they go up depending on a number of factors 5-alpha reductase has quite a strong genetic component so some men are very strong 5-alpha reductase producers and they're going to make a lot of DHT by the way this is responsible for one of the side effects of testosterone which is hair loss so a lot of hair loss is driven by DHT and the Androgen receptor
you can take a five Alpha reductase inhibitor uh so those are drugs that block the conversion of testosterone to dihydrotestosterone which is a more potent Androgen and that's the that's the Androgen that's driving Androgen specific hair loss
the unfortunate reality inherently in the name of what it is is what is causing it, which is androgenic androgen mediated alipcia. So the miniaturaturization of hair follicles mediated by androgens primarily the one that is the most potent in its androgenic activity which is DHT and these hormones it's not just like they convert and then have like in the in the blood or like at the liver or something there is like tissue specific concentrations of enzymes that are more prominent and in particular in the skin in the scalp especially too you will have there's way more five alpha reductase density in uh men for converting testosterone to DHT.
Typically it's pattern hair loss, miniaturization of the hair follicle. And if a lot